Prevalence Of Vitamin D Deficiency In Type 1 Diabetes Mellitus And Effect On Insulin Requirement After Supplementation With Vitamin D - A Pilot Study

Prevalence Of Vitamin D Deficiency In Type 1 Diabetes Mellitus And Effect On Insulin Requirement After Supplementation With Vitamin D - A Pilot Study

Approval Date: 12/31/1969

Principal Investigator: Peter Gerrits, M.D.

Vitamin D is a strong regulator of our immune system and is involved in regulating cell growth and change. Vitamin D helps in controlling normal endocrine function of the pancreas, this is done by binding to nuclear receptors. Vitamin D decreases the destruction of cells in the pancreas. By preventing cell destruction it can prevent autoimmune diabetes. Vitamin D is important for both insulin (the hormone that regulates the sugar in blood) secretion and sensitivity. Insulin secretion depends on changes in calcium. Vitamin D regulates calcium, and then the calcium helps with the insulin secretion. If the vitamin D level is too low in the blood then the balance of calcium is altered, which can interfere with insulin secretion. In current clinical practice vitamin D levels are not routinely monitored in diabetics.

Eligibility:

"Each study has its own guidelines for who can participate, called 'eligibility criteria.' Below is a partial list of criteria for acceptance into the research study. Only the study doctor can make the determination that you meet all eligibility criteria."

• New onset Type 1 Diabetic children who are receiving care from Dr. Gerrits, endocrinology group.

Contact Person:
Jeni DeRidder, RN, BSN
248-898-4578

Beth Kring, RN, BSN
248-898-4578

Status of Clinical Trial:
open and enrolling